Hikari Otabi, PhD

PUBLICATIONS

Journal Publications

• 2026
• Nest-building motivation in acute social defeat stress model mice: Effect of a low-temperature environment
  Hikari Otabi, Chiho Kozawa, Atsushi Toyoda
  Applied Animal Behaviour Science 301, 107034. 2026.
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• Female-biased vulnerability to transgenerational impact of paternal early-life stress
  Ichiro Ishikawa, Ken-ichi Ohta, Motoharu Imai, Masakazu Ishikawa, Haruki Kumei, Makoto Kashima, Ube Fugo, Shingo Suzuki, Hikari Otabi, Takanori Miki, Yu Nakamura
  Psychoneuroendocrinology 186, 107773. 2026.
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• Time-Dependent Effect of BDNF on the Transcriptomes of Cortical Neurons: Induction of Matrix Metalloproteases by BDNF
  Anna Kawai, Shingo Suzuki, Hajime Shigeto, Saki Akigawa, Ken-Ichi Ohta, Hikari Otabi, Takanori Miki
  Journal of Neurochemistry 170(3). 2026.
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• 2025
• Effects of attenuated TrkB signaling on the medial prefrontal cortex during early brain development: A comparative study using the maternal separation model
  Ken-Ichi Ohta, Hidetoshi Ujihara, Haruki Kumei, Shingo Suzuki, Hikari Otabi, Katsuhiko Warita, Takanori Miki
  Behavioural Brain Research 495, 115790. 2025.
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• 2024
• An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life
  Kanako Irie, Ken-ichi Ohta, Hidetoshi Ujihara, Chihiro Araki, Kodai Honda, Shingo Suzuki, Katsuhiko Warita, Hikari Otabi, Haruki Kumei, Shinji Nakamura, Kosuke Koyano, Takanori Miki, Takashi Kusaka
  Frontiers in Neuroscience 17. 2024.
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• 2023
• Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
  Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, ..., Hikari Otabi, ..., Tsuyoshi Miyakawa
  eLife. 2023.
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• Maternal separation early in life induces excessive activity of the central amygdala related to abnormal aggression
  Ken-ichi Ohta, Chihiro Araki, Hidetoshi Ujihara, Keizo Iseki, Shingo Suzuki, Hikari Otabi, Haruki Kumei, Katsuhiko Warita, Takashi Kusaka, Takanori Miki
  Journal of Neurochemistry 167(6), 778-794. 2023.
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• Development of a panel for detection of pathogens in xenotransplantation donor pigs
  Hikari Otabi, Hiroto Miura, Haruka Uryu, Rana Kobayashi-Harada, Kanako Abe, Kazuaki Nakano, Kazuhiro Umeyama, Koki Hasegawa, Takamitsu Tsukahara, Hiroshi Nagashima, Ryo Inoue
  Xenotransplantation, e12825. 2023.
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• 2022
• Studies of nest building behavior in social stress model of mouse
  Hikari Otabi (Corresponding author)
  Nihon Chikusan Gakkaiho 93 (2), 87-96. 2022. in Japanese
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• 2021
• Effects of Partially Hydrolyzed Guar Gum Supplementation on the Fecal Microbiotas of Piglets
  Ryo Inoue, Hikari Otabi, Taiga Yamashita, Naoya Takizawa, Toshinobu Kido, Akira Sugiyama, Makoto Ozeki, Aya Abe, Takamitsu Tsukahara
  Pathogens 10(11), 1420-1420. 2021.
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• Protein lactylation induced by neural excitation
  Hideo Hagihara, Hirotaka Shoji, Hikari Otabi, Atsushi Toyoda, Kaoru Katoh, Masakazu Namihira, Tsuyoshi Miyakawa
  Cell Reports 37(2), 109820-109820. 2021.
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• The Effects of Chronic Social Defeat Stress on Solid Gastric Emptying and Defecation in C57BL/6J Mice
  Naoko Moriya, Naoko Yamagishi, Tatsuhiko Goto, Hikari Otabi, Hiromi Nira-Kimoto, Atsushi Toyoda, Chise Suzuki
  Japan Agricultural Research Quarterly: JARQ 55(1), 77-83. 2021.
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• 2020
• Assessment of nest building and social interaction behavior in mice exposed to acute social defeat stress using a three‐dimensional depth camera
  Hikari Otabi, Tsuyoshi Okayama, Atsushi Toyoda
  Animal Science Journal 91(1), e13447. 2020
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• Reduction in BDNF from Inefficient Precursor Conversion Influences Nest Building and Promotes Depressive-Like Behavior in Mice
  Masami Kojima, Hikari Otabi, Haruko Kumanogoh, Atsushi Toyoda, Masahito Ikawa, Masaru Okabe, Toshiyuki Mizui
  International journal of molecular sciences 21(11), 2020
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• 2017
• The acute social defeat stress and nest-building test paradigm: A potential new method to screen drugs for depressive-like symptoms
  Hikari Otabi, Tatsuhiko Goto, Tsuyoshi Okayama, Daisuke Kohari, Atsushi Toyoda
  Behavioural Processes 135, 71-75. 2017
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• 2016
• Subchronic and mild social defeat stress alter mouse nest building behavior
  Hikari Otabi, Tatsuhiko Goto, Tsuyoshi Okayama, Daisuke Kohari, Atsushi Toyoda
  BEHAVIOURAL PROCESSES 122, 21-25. 2016
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